Anthrax Protein Variants

Anthrax toxin is a three-protein exotoxin secreted by virulent strains of the bacterium, Bacillus anthracis, the causative agent of anthrax. Anthrax toxin is composed of a cell-binding protein, known as protective antigen (PA), and two enzyme components, called edema factor (EF) and lethal factor (LF). Anthrax is caused by B. anthracis, a spore-forming, Gram positive, rod-shaped bacterium. The lethality of the disease is caused by the bacterium's two principal virulence factors: the polyglutamic acid capsule, which is anti-phagocytic, and the tripartite protein toxin, called anthrax toxin.

Filter X
Your Selection
Product Type
Antibody 
(1)
Protein 
(14)
Name
AGG-LFn-NLSLEELKD-GGGGSC 
(1)
D512K 
(1)
D683A, L685E, Y688K 
(1)
D683A, L685E, Y688K, C-terminal Cys 
(1)
D683A, L685E, Y688K; C-terminal sequence added: GSGSGSLPETGGHHHHHH 
(1)
E678A 
(1)
F427A 
(1)
Furin site, aa 164-176, RKKR, is changed to PGG 
(1)
K313R 
(1)
K562C; Furin site, aa 164-176, RKKR, is changed to PGG 
(1)
K563C 
(1)
L678A 
(1)
LFn-Pseudomonas exotoxin A domain III 
(1)
Wild-type 
(1)
View More >>
Antigen
poly-γ-D-glutamic acid (PGA) 
(1)
Clonality
Monoclonal 
(1)
Clone Name
8B10 
(1)
Reactivity
Reacts with PGA from B. anthracis and B. licheniformis 
(1)
Species Immunized
CD1 Mouse 
(1)
Loading...