This mouse IgG1 monoclonal antibody recognizes poly-γ-D-glutamic acid (PGA) of B. anthracis and B. licheniformis.
Inhalational anthrax is a serious biothreat. Effective antibiotic treatment of inhalational anthrax requires early diagnosis; the further the disease has progressed, the less the likelihood for cure. Current means for diagnosis such as blood culture require several days to a result and require advanced laboratory infrastructure. An alternative approach to diagnosis is detection of a Bacillus anthracis antigen poly-γ-D-glutamic acid (PGA), the capsular antigen of B. anthracis, that is shed into blood and can be detected by rapid immunoassay.
From the laboratory of Thomas R. Kozel, PhD, University of Nevada, Reno.
|Antigen:||poly-γ-D-glutamic acid (PGA)|
|Reactivity:||Reacts with PGA from B. anthracis and B. licheniformis|
|Species Immunized:||CD1 Mouse|
|Purification Method:||Recombinant Protein A sepharose|
|Buffer:||PBS, pH 7.4|
|Tested Applications:||ELISA, Western Blot, Lateral Flow Immunoassay|
|Storage:||-80C (avoid repeated freeze-thaw cycles)|
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