Brian J. Geiss, PhD, Colorado State University

Brian J. Geiss, PhD
Brian J. Geiss, PhD

A major focus of the Geiss laboratory is studying the biochemistry of flavivirus NS5 RNA capping enzyme. The capping enzyme is a multifunctional protein that forms the mature viral RNA cap that directs viral polyprotein translation and protects the viral genome from degradation.



  1. Weger-Lucarelli J, Duggal NK, Bullard-Feibelman K, Veselinovic M, Romo H, Nguyen C, Rückert C, Brault AC, Bowen RA, Stenglein M, Geiss BJ, Ebel GD. Development and Characterization of Recombinant Virus Generated from a New World Zika Virus Infectious Clone. J Virol. 2016 Dec 16;91(1). pii: e01765-16. Print 2017 Jan 1. Erratum in: J Virol. 2017 Mar 29;91(8):. PubMed PMID: 27795432
  2. Geiss BJ, Shimonkevitz LH, Sackal CI, Olson KE. Recombination-ready Sindbis replicon expression vectors for transgene expression. Virol J. 2007 Oct 26;4:112.PubMed PMID: 17963504; PubMed Central PMCID: PMC2164957.