Algirdas J. Jesaitis, PhD, Montana State University

Jesaitis
Algirdas J. Jesaitis, PhD

Research interests in the Jesaitis laboratory include: regulatory interactions of N-formyl peptide, reorganization of the plasma membrane, random sequence phage display analysis, immunocytochemical detection of lipid peroxidation, and structural and sunction analysis of the superoxide.

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References

  1. Burritt, J.B., Quinn, M.T., Jutila, M.A., Bond, C.W. and Jesaitis, A.J.Topological mapping of neutrophil cytochrome b epitopes with phage display libraries. J.Biol.Chem. 270:16974-16980, 1995.
  2. Burritt, J.B., Busse, S.C., Gizachew, D., Siemsen, D.W., Quinn, M.T., Bond, C.W., Dratz, E.A. and Jesaitis, A.J. Antibody imprint of a membrane protein surface: Phagocyte Flavocytochrome b. J Biol. Chem., 273:24847-52, 1998.
  3. Burritt,J.B., Foubert, T.R., Baniulis, D., Lord, C.L., Taylor, R.M., Mills, J.S., Roos, D., Parkos, C.A. and Jesaitis, A.J. Functional epitope on human neutrophil flavocytochrome b558. J.Immunol. 170:6082-6089. 2003.
  4. Taylor, R.M, Burritt, J.B., Baniulis, D., Lord, C.I., Dinauer, M.C., Parkos, C.A. and Jesaitis, A.J. Characterization of Six Monoclonal Antibodies to the p22phox Subunit of Human Phagocyte Flavocytochrome b: Site Specific Inhibitors of NADPH Oxidase Activity and Probes for Analysis of Flavocytochrome b Surface Structure and Topology. J Immunol. 173:7349-57, 2004.
  5. Baniulis, D., Burritt, J.B., Taylor, R.M, Dinauer, M.C., Heyworth, P.G., Parkos, C.A., Magnusson, K.-E., Jesaitis, A.J. Monoclonal antibody CL5 recognizes the amino terminal domain of human phagocyte flavocytochrome b558 large subunit gp91phox. Eur. J. Hematology 74(4):337-47, 2005.
  6. Danas B., Yoko N., William M. Nauseef, Botond Banfi Guangjie Cheng, David J. Lambeth, James B. Burritt, Ross M. Taylor, Algirdas J. Jesaitis. Evaluation of two anti-gp91phox antibodies as immunoprobes for Nox family proteins: mAb 54.1 recognizes recombinant full-length Nox2, Nox3 and the C-terminal domains of Nox1-4 and cross-reacts with GRP 58. Biochimica et Biophysica Acta 1752 (2005) 186 â?? 196.
  7. Stie, J. Jesaitis, A.V., Burritt, J.B., Taylor, R.M., Lord, C.I., Gripentrog, J.M. and Jesaitis, A.J.Localization of hCAP-18 on the Surface of Chemoattractant-stimulated Human Granulocytes: Analysis Using Two Novel hCAP-18-Specific Monoclonal Antibodies J.Leuk. Biol. 82:161-72. 2007.
  8. Taylor, R.M. Jesaitis, A.J.Immunoaffinity purification of human phagocyte flavocytochrome b and analysis of conformational dynamics. Methods Mol Biol. 2007;412:429-37, 2007.
  9. Maaty WS, Lord CI, Gripentrog JM, Riesselman M, Keren-Aviram G, Liu T, Dratz EA, Bothner B, Jesaitis AJ. Identification of C-terminal phosphorylation sites of N-formyl peptide receptor-1 (FPR1) in human blood neutrophils. J Biol Chem. 2013 Sep 20;288(38):27042-58.
  10. Schneider EH, Weaver JD, Gaur SS, Tripathi BK, Jesaitis AJ, Zelenka PS, Gao JL, Murphy PM. The leukocyte chemotactic receptor FPR1 is functionally expressed on human lens epithelial cells. J Biol Chem. 2012 Nov 23;287(48):40779-92.
  11. Riesselman M, Miettinen HM, Gripentrog JM, Lord CI, Mumey B, Dratz EA, Stie J, Taylor RM, Jesaitis AJ. C-terminal tail phosphorylation of N-formyl peptide receptor: differential recognition of two neutrophil chemoattractant receptors by monoclonal antibodies NFPR1 and NFPR2. J Immunol. 2007 Aug 15;179(4):2520-31.