Gail M. Seigel, PhD, University at Buffalo

Gail M. Seigel, PhD
Gail M. Seigel, PhD

The Seigel laboratory's primary research focus is the study of cancer stem cells in retinoblastoma. In particular, they study ocular stem cells and precursor cells in order to isolate, establish and characterize cell lines with basic and clinical applications in Ophthalmology.

You can now order Dr. Seigel's book Academania: My Life in the Trenches of Biomedical Research.


Read Dr. Seigel's related blog posts:
On the Road to Retinal Cells
What the Heck are Cytospins?




  1. Seigel GM, Manohar S, Yingying, B, Ding D and Salvi R. An immortalized microglial cell line (Mocha) derived from rat cochlea. Mol. Cell. Neurosci. 85 (2017) 202-210).
  2. Seigel, GM, 1996. Establishment of an E1A-immortalized rat retinal cell culture, In Vitro Cell. Devel. Biol. 32: 66-68.
  3. Seigel, GM, Mutchler, A.L., and E.L. Imperato.  1996. Expression of glial cell markers in a retinal precursor cell line Mol. Vis. 2: 2.
  4. Seigel, GM, Takahashi, M., Adamus, G., McDaniel, T. 1998. Intraocular transplantation of E1A-immortalized retinal precursor cells. Cell Transplant. 7 (6): 559-566.
  5. Seigel, GM, Sun, W, Wang, J., Hershberger, DH, Campbell, LM, Salvi, RJ.  2004. Neuronal gene expression and function in the growth-stimulated R28 retinal precursor cell line.  Curr. Eye Res., 28 (4):257-269.
  6. Zacharias LC, Estrago-Franco MF, Ramirez C, Kenney MC, Takahashi WY, Seigel GM, Kuppermann BD. The effects of commercially available preservative-free FDA-approved triamcinolone (Triesence®) on retinal cells in culture. J Ocul Pharmacol Ther. 2011 Apr;27(2):143-50.