Anti-MAP kinase 1/Erk2 [1B3B9] Antibody

This IgG2a mouse monoclonal antibody [1B3B9] was generated against HPLC purified murine recombinant mitogen-activated protein kinase 1 (MAPK1) and is reactive against avian, human, mouse and rat MAP kinase 1/Extracellular signal-regulated kinase2 (ERK2).

Highlights

  • Reacts with avian, human, mouse and rat MAP kinase 1/ERK2
  • Suitable for Western Blot applications

ERK2 is activated by mitogen-activated protein kinase 2 (MEK2), which phosphorylates neighboring threonine 183 and tyrosine 185 residues. ERK2 is a serine/threonine kinase that phosphorylates MAP2 and myelin basic protein. This kinase is an important proximal component of the MAP kinase pathway involved in transmitting the signals from growth factors, neurotransmitters and hormones at the cell surface to the transcriptional events in the nucleus.

From the laboratory of Michael J. Weber, PhD, University of Virginia.

The Investigator's Annexe Part of The Investigator's Annexe program.

Catalog Number Product Size AVAILABILITY Price Qty
EG1901
Anti-MAP kinase 1/Erk2 [1B3B9] Antibody
100ug 2-3 weeks
Regular Price:$269.00
Specifications

Product Type: Antibody
Alternative Name(s): Mitogen-activated protein kinase kinase 2; ERK activator kinase 2; FLJ26075; MAP kinase kinase 2; MAP2K2; MAPK/ERK kinase 2; MAPKK 2; MAPKK2; MEK 2; MEK2; mitogen-activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2, p45; MKK2; MP2K2; PRKMK2
Accession ID: NM_002745
Antigen: MAP Kinase 1/ERK2
Molecular Weight: 42 kDa
Isotype: IgG2a
Clonality: Monoclonal
Clone Name: 1B3B9
Reactivity: Avian, mouse, rat and human
Immunogen: HPLC purified murine recombinant MAP Kinase
Species Immunized: Mouse
Purification Method: Protein G Affinity Chromatography
Buffer: 0.1M Sodium Phosphate, pH 7.4, 0.15M NaCl, 0.05% (w/v) Sodium Azide
Tested Applications: WB
Storage: -20C
Shipped: Cold packs

Documentation

Notes

At low concentration, preferentially reacts with unphosphorylated enzyme.

Provider
From the laboratory of Michael J. Weber, PhD, University of Virginia.
References
  1. Kumar NV1, Bernstein LR. Ten ERK-related proteins in three distinct classes associate with AP-1 proteins and/or AP-1 DNA. J Biol Chem. 2001 Aug 24;276(34):32362-72.

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