This monoclonal antibody was generated against purified recombinant human interferon regulatory factor 3 (IRF3) and is specific for human IRF3.
IRF3 is a member of the interferon regulatory transcription factor (IRF) family. IRF3 has been shown to contain several functional domains including a nuclear export signal, a DNA-binding domain, a C-terminal IRF association domain and several regulatory phosphorylation sites. IRF3 plays an important role in the innate immune system's response to viral infection.
From the laboratory of Adolfo Garcia-Sastre, PhD, Icahn School of Medicine at Mount Sinai.
Part of The Investigator's Annexe program.
|Molecular Weight:||47.2 kDa|
|Immunogen:||Recombinant protein derived from the C-terminal region of human IRF3|
|Purification Method:||Protein A|
|Tested Applications:||WB (1:1000), ELISA, IF (1:200), IHC|
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