Anti-IRF3 [17C2] Antibody

This monoclonal antibody was generated against purified recombinant human interferon regulatory factor 3 (IRF3) and is specific for human IRF3.

IRF3 is a member of the interferon regulatory transcription factor (IRF) family. IRF3 has been shown to contain several functional domains including a nuclear export signal, a DNA-binding domain, a C-terminal IRF association domain and several regulatory phosphorylation sites. IRF3 plays an important role in the innate immune system's response to viral infection.

From the laboratory of Adolfo Garcia-Sastre, PhD, Icahn School of Medicine at Mount Sinai.

The Investigator's Annexe Part of The Investigator's Annexe program.

Catalog Number Product Size AVAILABILITY Price Qty
EMS006
Anti-IRF3 [17C2] Antibody
100ug (1mg/mL) In stock
Regular Price:$328.00
Specifications

Product Type: Antibody
Antigen: Human IRF3
Accession ID: Q14653
Molecular Weight: 47.2 kDa
Isotype: IgG2a
Clonality: Monoclonal
Clone Name: 17C2
Reactivity: Human
Immunogen: Recombinant protein derived from the C-terminal region of human IRF3
Species Immunized: Mouse
Purification Method: Protein A
Tested Applications: WB (1:1000), ELISA, IF (1:200), IHC
Concentration: 1 mg/mL
Storage: -20C
Shipped: Cold packs

Provider
From the laboratory of Adolfo Garcia-Sastre, PhD, Icahn School of Medicine at Mount Sinai.
References
  1. Garcia-Sastre, et al. Manuscript in progress.
  2. Mathers C, Schafer X, Martínez-Sobrido L, Munger J. The human cytomegalovirus UL26 protein antagonizes NF-κB activation. J Virol. 2014 Dec;88(24):14289-300. doi: 10.1128/JVI.02552-14. PubMed PMID: 25275128; PubMed Central PMCID: PMC4249132. View Article

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