Human Lc3B-6His (LC3B)
LC3 is a central protein in the autophagy pathway where it functions in autophagy substrate selection and autophagosome biogenesis. LC3 is the most widely used marker of autophagosomes. Microtubule-associated proteins 1A/1B light chain 3B (LC3B) is a protein that in humans is encoded by the MAP1LC3B gene. This peptide can be use in structural studies and in studying autophagy machinery.
From the laboratory of Scott D. Ryan, PhD, University of Guelph.
LC3 is a central protein in the autophagy pathway where it functions in autophagy substrate selection and autophagosome biogenesis. LC3 is the most widely used marker of autophagosomes. Microtubule-associated proteins 1A/1B light chain 3B (LC3B) is a protein that in humans is encoded by the MAP1LC3B gene. This peptide can be use in structural studies and in studying autophagy machinery.
From the laboratory of Scott D. Ryan, PhD, University of Guelph.
Specifications
| Product Type: | Protein |
| Name: | recombinant human LC3B-6His |
| Alternative Name(s): | LC3B |
| Accession ID: | Q9GZQ8, 81631 |
| Source: | Human, expressed in E. coli BL21 (DE3) CP+ |
| Molecular Weight: | 16,714 |
| Fusion Tag(s): | MGSS-6XHis (N-terminal) |
| Purity: | >95 %, purified by ion-exchange chromatography followed by reverse phase chromatography |
| Buffer: | 10mM KPB pH 7.4 |
| Storage: | -80C |
| Shipped: | Dry Ice |
Provider
From the laboratory of Scott D. Ryan, PhD, University of Guelph.
References
- ARyan, T., Bamm, V.V., Stykel, M.G., Coackley, C.L., Humphries, K.M., Jamieson-Williams, R., Ambasudhan, R., Mosser, D.D., Lipton, S.A., Harauz, G., et al. (2018). Cardiolipin exposure on the outer mitochondrial membrane modulates α-synuclein. Nat. Commun 9, 1-17. doi:10.1038/s41467-018-03241-9.
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