Human Lc3B-6His (LC3B)

LC3 is a central protein in the autophagy pathway where it functions in autophagy substrate selection and autophagosome biogenesis. LC3 is the most widely used marker of autophagosomes. Microtubule-associated proteins 1A/1B light chain 3B (LC3B) is a protein that in humans is encoded by the MAP1LC3B gene. This peptide can be use in structural studies and in studying autophagy machinery.

From the laboratory of Scott D. Ryan, PhD, University of Guelph.

Catalog Number Product Size AVAILABILITY Price Qty
EGP001
Human Lc3B-6His (LC3B)
0.5mg 1-2 weeks
Regular Price:$500.00
Specifications

Product Type: Protein
Name: recombinant human LC3B-6His
Alternative Name(s): LC3B
Accession ID: 81631
Source: Human, expressed in E. coli BL21 (DE3) CP+
Molecular Weight: 16,714
Fusion Tag(s): MGSS-6XHis (N-terminal)
Purity: >95 %, purified by ion-exchange chromatography followed by reverse phase chromatography
Buffer: 10mM KPB pH 7.4
Storage: -80C
Shipped: Dry Ice

Provider
From the laboratory of Scott D. Ryan, PhD, University of Guelph.
References
  1. ARyan, T., Bamm, V.V., Stykel, M.G., Coackley, C.L., Humphries, K.M., Jamieson-Williams, R., Ambasudhan, R., Mosser, D.D., Lipton, S.A., Harauz, G., et al. (2018). Cardiolipin exposure on the outer mitochondrial membrane modulates α-synuclein. Nat. Commun 9, 1-17. doi:10.1038/s41467-018-03241-9.

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