This mouse IgG2a monoclonal antibody (clone 21C3) was generated against virus and is specific for the Hemagglutinin (HA) protein of influenza B Panama/45/90.
Influenzavirus B is a genus in the virus family Orthomyxoviridae. Influenza B viruses are only known to infect humans and seals. This limited host and range is apparently responsible for the lack of Influenzavirus B-caused influenza pandemics, in contrast with those caused by the morphologically similar Influenzavirus A. Haemagglutinin causes red blood cells to clump together and binds the virus to the infected cell. In Neuraminidase are a type of glycoside hydrolase enzyme which help to move the virus particles through the infected cell and assist in budding from the host cells.
From the laboratory of Thomas M. Moran, PhD, Icahn School of Medicine at Mount Sinai.
Part of The Investigator's Annexe program.
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