This mouse IgG1 monoclonal antibody [1G11] was generated against recombinant protein and recognizes human and rabbit early endosome antigen 1 (EEA1).
Early endosome antigen 1 (EEA1) has been show to bind phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. Antibodies against EEA1 has been found in patients with subacute cutaneous lupus erythematosus and other autoimmune diseases.
From the laboratory of Marvin J. Fritzler, MD, PhD, University of Calgary.
Part of The Investigator's Annexe program.
|Alternative Name(s):||MST105; MSTP105; ZFYVE2; early endosome antigen 1; early endosome antigen 1, 162kD; early endosome-associated protein; Endosome-associated protein p162; MSTP105; ZFYVE2; ZFYVE2MST105; Zinc finger FYVE domain-containing protein 2|
|Antigen:||EEA1 (Early endosome antigen)|
|Accession ID:||Q15075, NP_003557|
|Molecular Weight:||162 kDa|
|Reactivity:||Human and rabbit|
|Buffer:||Cell media supernatant|
|Tested Applications:||WB (1:100-1:500), IF|
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