Melinda A. Brindley, PhD, University of Georgia

Melinda A. Brindley, PhD
Melinda A. Brindley, PhD

The Brindley Lab studies how viruses enter cells and begin the process of infection. Current projects involve characterizing how numerous enveloped viruses acquire phosphatidylserine in their lipid envelopes to facilitate binding, internalization, and budding.

 

Products

References

  1. Havranek KE, Jimenez AR, Acciani MD, Lay Mendoza MF, Reyes Ballista JM, Diaz DA, Brindley MA. SARS-CoV-2 Spike Alternations Enhance Pseudoparticle Titers and Replication-Competent VSV-SARS-CoV-2 Virus. Viruses. 2020 Dec 18; 12(12). PMID: 33353101
  2. Acciani MD, Lay-Mendoza MF, Havranek KE, Duncan AM, Iyer H, Linn OL, Brindley MA. Ebola virus requires phosphatidylserine scrambling activity for efficient budding and optimal infectivity. bioRxiv 2020.03.16.994012; doi:org/10.1101/2020.03.16.994012
  3. Lay Mendoza MF, Acciani MD, Levit CN, Santa Maria C, Brindley MA. Monitoring viral entry in real-time using a luciferase recombinant vesicular stomatitis virus producing SARS-CoV-2, EBOV, LASV, CHIKV, and VSV glycoproteins. Viruses. 2020 Dec 17; 12(12). PMID: 33348746