Francisco Vega, MD, PhD, University of Miami
Francisco Vega, MD, PhD
Dr. Vega's research has demonstrated that Hedgehog signaling is aberrantly activated in high-grade B- and T-cell lymphomas and that this aberrant behavior contributes to deregulated autonomous cell growth and to the survival and chemotolerance of lymphoma cells.
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References
- Qu C, Kunkalla K, Vaghefi A, Frederiksen JK, Liu Y, Chapman JR, Blonska M, Bernal-Mizrachi L, Alderuccio JP, Lossos IS, Landgraf R, Vega F. Smoothened stabilizes and protects TRAF6 from degradation: A novel non-canonical role ofsmoothened with implications in lymphoma biology. Cancer Lett. 2018 Nov 1;436:149-158.
