HT (B-Cell Lymphoma) Cell Lines
HT (B-cell lymphoma) control cell line and TNF receptor associated factor 6 (TRAF6) Knock Down HT (B-Cell Lymphoma) Cell Line were stablished from the ascitic effusion of a 70-year-old man with B cell non-Hodgkin lymphoma (B-NHL) in 1983 (diffuse large cell lymphoma).
B-Cell lymphoma is a cancer that forms in white blood cells called lymphocytes. Most B-cell lymphomas are non-Hodgkin's lymphoma. TNF receptor associated factors also known as TRAFs are a family of proteins primarily involved in the regulation of inflammation, antiviral responses and apoptosis. There are 7 mammalian TRAFs and they mediates interactions with other signaling components such as the transmembrane TNF receptors and CD40.
From the laboratory of Francisco Vega, MD, PhD, University of Miami.
HT (B-cell lymphoma) control cell line and TNF receptor associated factor 6 (TRAF6) Knock Down HT (B-Cell Lymphoma) Cell Line were stablished from the ascitic effusion of a 70-year-old man with B cell non-Hodgkin lymphoma (B-NHL) in 1983 (diffuse large cell lymphoma).
B-Cell lymphoma is a cancer that forms in white blood cells called lymphocytes. Most B-cell lymphomas are non-Hodgkin's lymphoma. TNF receptor associated factors also known as TRAFs are a family of proteins primarily involved in the regulation of inflammation, antiviral responses and apoptosis. There are 7 mammalian TRAFs and they mediates interactions with other signaling components such as the transmembrane TNF receptors and CD40.
From the laboratory of Francisco Vega, MD, PhD, University of Miami.
| Catalog Number | Product | DataSheet | Size | AVAILABILITY | Price | Qty |
|---|
| Product Type: | Cell Line |
| Cell Type: |
HT (B-cell lymphoma) TRAF6 Knock Down HT (B-Cell Lymphoma) |
| Morphology: | Suspension |
| Organism: | Human |
| Source: | Ascitic effusion |
| Biosafety Level: | BSL 2 |
| Growth Conditions: | RPMI+10% FBS+ Antibiotics + 1µg/ml puromycin |
| Subculturing: | Doubling time 30-40hrs |
| Cryopreservation: | 95% complete media + 5% DMSO |
| Age: | 70-year-old male |
| Comments: | 1ug/mL puromycin reuired for selection. |
| Storage: | Liquid Nitrogen |
| Shipped: | Dry Ice |
From the laboratory of Francisco Vega, MD, PhD, University of Miami.
- Qu C, Kunkalla K, Vaghefi A, Frederiksen JK, Liu Y, Chapman JR, Blonska M, Bernal-Mizrachi L, Alderuccio JP, Lossos IS, Landgraf R, Vega F. Smoothened stabilizes and protects TRAF6 from degradation: A novel non-canonical role ofsmoothened with implications in lymphoma biology. Cancer Lett. 2018 Nov 1;436:149-158.
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