Thomas U. Schwartz, PhD, Massachusetts Institute of Technology
Thomas U. Schwartz, PhD
Research in the Schwartz lab aims at understanding protein function on the basis of atomic structure determination using X-ray crystallography as an important tool. Their focal point is the elucidation of the structure and function of the Nuclear Pore Complex (NPC), the gateway into and out of the cell's nucleus and thus of central importance for separating transcription and translation. They employ an integrative approach to this research area combining structure determination with biochemical, biophysical, cell biological and genetic methods.
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References
- Andersen KR, Leksa NC, Schwartz TU. Optimized E. coli expression strain LOBSTR eliminates common contaminants from His-tag purification. Proteins. 2013 Nov;81(11):1857-61.
