Anti-poly-γ-D-glutamic acid (PGA) [8B10] Antibody

This mouse IgG1 monoclonal antibody recognizes poly-γ-D-glutamic acid (PGA) of B. anthracis and B. licheniformis.

Highlights

  • Binds to poly-γ-D-glutamic acid (PGA) from B. anthracis and B. licheniformis
  • Suitable for ELISA, Western Blot, and lateral flow immunoassay applications

Inhalational anthrax is a serious biothreat. Effective antibiotic treatment of inhalational anthrax requires early diagnosis; the further the disease has progressed, the less the likelihood for cure. Current means for diagnosis such as blood culture require several days to a result and require advanced laboratory infrastructure. An alternative approach to diagnosis is detection of a Bacillus anthracis antigen poly-γ-D-glutamic acid (PGA), the capsular antigen of B. anthracis, that is shed into blood and can be detected by rapid immunoassay.

From the laboratory of Thomas R. Kozel, PhD, University of Nevada, Reno.

Catalog Number Product Size AVAILABILITY Price Qty
ENR003
Anti-poly-γ-D-glutamic acid (PGA) [8B10] Antibody, 100ug
100ug In stock
Price: $299.00
Specifications
Product Type: Antibody
Antigen: poly-γ-D-glutamic acid (PGA)
Isotype: IgG1
Clonality: Monoclonal
Clone Name: 8B10
Reactivity: Reacts with PGA from B. anthracis and B. licheniformis
Species Immunized: CD1 Mouse
Purification Method: Recombinant Protein A sepharose
Buffer: PBS, pH 7.4
Tested Applications: ELISA, Western Blot, Lateral Flow Immunoassay
Storage: -80C (avoid repeated freeze-thaw cycles)
Shipped: Cold packs
Provider
From the laboratory of Thomas R. Kozel, PhD, University of Nevada, Reno.
References
  1. Gates-Hollingsworth, Marcellene A. et al. "Immunoassay for Capsular Antigen of Bacillus Anthracis Enables Rapid Diagnosis in a Rabbit Model of Inhalational Anthrax." Ed. Ramin M. Hakami. PLoS ONE 10.5 (2015): e0126304. PMC. Web. 9 Oct. 2018.

If you publish research with this product, please let us know so we can cite your paper.

 
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