Mannan-Binding Lectin Serine Protease 2 (MASP-2)

Mannan-Binding Lectin Serine Protease 2 (MAPS-2) expressed in E. Coli.

MASP-2 is involved in the complement system. MASP-2 is very similar to the C1s molecule, of the classical complement pathway, and they are thought to have a common evolutionary ancestor. When the carbohydrate-recognizing heads of MBL bind to specifically arranged mannose residues on the surface of a pathogen, MASP-2 is activated to cleave complement components C4 and C2 into C4a, C4b, C2a, and C2b.

From the laboratory of Lakshmi C. Wijeyewickrema, PhD, La Trobe University.

Catalog Number Product Size AVAILABILITY Price Qty
ETL004
Mannan-Binding Lectin Serine Protease 2 (MASP-2)
20ug 4-6 weeks
Price: $500.00
Specifications
Product Type: Protein
Name: MASP2CCP12SP
Accession ID: O00187
Source: Escherichia coli
Molecular Weight: 43744.6 (Predicted); around 16kDa and 26kDa on SDS-PAGE under reducing condition
Amino Acid Sequence: T287-F686
Purity: >95%, by SDS-PAGE under reducing conditions and visualized by Coomassie Blue Stain
Buffer: 20 mM Tris, 150mM Nacl, pH7.5
Storage: -80C
Shipped: Dry Ice
Data
SDS-PAGE
Provider
From the laboratory of Lakshmi C. Wijeyewickrema, PhD, La Trobe University.
References
  1. Duncan RC, Mohlin F, Taleski D, Coetzer TH, Huntington JA, Payne RJ, Blom AM, Pike RN, Wijeyewickrema LC. Identification of a catalytic exosite for complement component C4 on the serine protease domain of C1s. J Immunol. 2012 Sep 1;189(5):2365-73.

If you publish research with this product, please let us know so we can cite your paper.

 
Loading...
Loading...