Mannan-Binding Lectin Serine Protease 2 (MAPS-2) expressed in E. Coli.
MASP-2 is involved in the complement system. MASP-2 is very similar to the C1s molecule, of the classical complement pathway, and they are thought to have a common evolutionary ancestor. When the carbohydrate-recognizing heads of MBL bind to specifically arranged mannose residues on the surface of a pathogen, MASP-2 is activated to cleave complement components C4 and C2 into C4a, C4b, C2a, and C2b.
From the laboratory of Lakshmi C. Wijeyewickrema, PhD, La Trobe University.
|Molecular Weight:||43744.6 (Predicted); around 16kDa and 26kDa on SDS-PAGE under reducing condition|
|Amino Acid Sequence:||T287-F686|
|Purity:||>95%, by SDS-PAGE under reducing conditions and visualized by Coomassie Blue Stain|
|Buffer:||20 mM Tris, 150mM Nacl, pH7.5|
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