Mannan-Binding Lectin Serine Protease 1 (MASP-1)

Mannan-Binding Lectin Serine Protease 1 (MAPS-1) expressed in E. Coli.

MASP-1 is a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. MASP-1 is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. MASP-1 is also able to cleave fibrinogen and factor XIII and may be involved in coagulation.

From the laboratory of Lakshmi C. Wijeyewickrema, PhD, La Trobe University.

Catalog Number Product Size AVAILABILITY Price Qty
ETL003
Mannan-Binding Lectin Serine Protease 1 (MASP-1)
20ug 4-6 weeks
Price: $500.00
Specifications
Product Type: Protein
Name: MASP1CCP12SP Enzyme
Accession ID: P48740
Source: Escherichia coli
Molecular Weight: 45072.58 (Predicted), around 16kDa and 28kDa on SDS-PAGE under reducing condition
Amino Acid Sequence: G298-N699
Purity: >95%, by SDS-PAGE under reducing conditions and visualized by Coomassie Blue Stain
Buffer: 20 mM Tris, 150mM Nacl, pH7.5
Storage: -80C
Shipped: Dry Ice
Data
SDS-PAGE
Provider
From the laboratory of Lakshmi C. Wijeyewickrema, PhD, La Trobe University.
References

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