Anti-Anopheles gambiae Aminopeptidase [AgAPN2] Antibody

This rabbit IgG polyclonal antibody was generated against a peptide corresponding to amino acids 228-843 of Anopheles gambiae Aminopeptidase and recognizes A. gambiae Aminopeptidase.

Highlights:

  • Reacts with A. gamiae Aminopeptidase
  • Useful in R&D involving Anopheles, for identification and validation of targets for insect control by - d-endotoxins, and other biochemical/biological methods
  • Several species of Anopheles are disease vectors (malaria, canine heartworm, filariasis, O’nyong’nyong)
  • Recommended for Western Blot, Immunofluorescence, Immunohistochemistry and ELISA applications

Aminopeptidase is an enzyme that catalyzes the breakdown of a peptide, removing the amino acyl residue at the amino end of the chain (that is, an N-exopeptidase); found in intestinal secretions. They are widely distributed throughout both animal and plant kingdoms and are found in many subcellular organelles, in cytoplasm, and as membrane components.

From the laboratory of Michael J. Adang, PhD, University of Georgia.

The Investigator's Annexe Part of The Investigator's Annexe program.

Catalog Number Product Size AVAILABILITY Price Qty
EGA028
Anti-Anopheles gambiae Aminopeptidase [AgAPN2] Antibody, 50uL
50uL In stock
Price: $321.00
Contact us for details.
Specifications
Product Type: Antibody
Antigen: Aminopeptidase from A. gambiae
Molecular Weight: 106 kDa
Isotype: IgG
Clonality: Polyclonal
Clone Name: Anti-AgAPN2
Reactivity: A. gambiae, Very likely other members of the Anopheles genus, less likely Culex. Possibly, other insects/particularly mosquitoes
Immunogen: Peptide
Species Immunized: NZW Rabbit
Epitope: 70-kDa peptide encoding amino acid residues 228 to 843
Purification Method: Sepharose beads/ethanolamine buffer, pH 8
Method Used to Determine Concentration: Bio-Rad protein assay using bovine serum albumin (BSA) as standard
Buffer: Na2CO3/NaHCO3, pH 9.6
Tested Applications: WB, IF, IHC, ELISA
Storage: -80C
Shipped: Dry ice
Provider
From the laboratory of Michael J. Adang, PhD, University of Georgia.
References
  1. Zhang, R., Hua, g., Andacht, T.M., and Adang, M.J. 2008. A 106-kDa aminopeptidase is a putative receptor for Bacillus thuringiensis Cry11Ba toxin in the mosquito Anopheles gambiae genome. Biochemistry. 47(43). 11263-11272.
  2. Zhang, R., Hua, G., Urbauer, J.L., and Adang, M.J. (2010) Synergistic and inhibitory effects of aminopeptidase peptides on Bacillus thuringiensis Cry11Ba toxicity in the mosquito Anopheles gambiae. Biochemistry. 49(39):8512-9.

If you publish research with this product, please let us know so we can cite your paper.

 
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