Anti-AJUBA [3198] Antibody

This rabbit IgG polyclonal antibody was generated against LIM domain-containing protein ajuba (AJUBA) and recognizes mouse AJUBA.

Highlights:

  • Recognizes mouse AJUBA
  • Recommended for Western Blot, Immunoprecipitation, Immunofluorescence, and CHIP applications

AJUBA is a scaffold protein which is a part of numerous protein complexes and controls several cellular processes such as determination of cell fate, cytoskeletal organization, gene transcription, cell adhesion, differentiation, cell cycle and motility. AJUBA regulates Aurora A kinase during mitosis. AJUBA is an effector in IL-1 signaling pathway and is able to modulate IL-1-induced NFKB1 activation by regulating the integrity and activity of the PRKCZ-SQSTM1-TRAF6 multiprotein signaling complex. AJUBA is a HDAC-dependent corepressor for a subset of GFI1 target genes. AJUBA downregulates E-cadherin transcription in a SNAI1 and SNAI2/SLUG-dependent manner.

From the laboratory of Frank J. Rauscher, III, PhD, The Wistar Institute.

The Investigator's Annexe Part of The Investigator's Annexe program.

Catalog Number Product Size AVAILABILITY Price Qty
EWI011
Anti-AJUBA [3198] Antibody, 100ug
100ug In stock
Price: $321.00
Specifications
Product Type: Antibody
Accession ID: HGNC: 20250; Ensembl: ENSG00000129474; Entrez Gene: 84962; OMIM: 609066; UniProtKB: Q96IF1
Antigen: AJUBA
Molecular Weight: 57 kDa
Isotype: IgG
Clonality: Polyclonal
Clone Name: 3198
Reactivity: Mouse
Immunogen: Recombinant AJUBA protein
Species Immunized: Rabbit
Purification Method: Affinity purified
Buffer: BSA/sodium azide
Tested Applications: WB (1:1000), IP, IF, CHIP
Concentration: 1mg/mL
Storage: -20C, avoid freeze thaw cycles
Shipped: Cold packs
Provider
From the laboratory of Frank J. Rauscher, III, PhD, The Wistar Institute.
References
  1. Hou Z, Peng H, White DE, Negorev DG, Maul GG, Feng Y, Longmore GD, Waxman S, Zelent A, Rauscher FJ 3rd. LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):2938-43. doi: 10.1073/pnas.0908656107.

If you publish research with this product, please let us know so we can cite your paper.

 
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