Anti-PECAM-1, Cytoplasmic Domain [MBC 235.1] Antibody
![Anti-PECAM-1, Cytoplasmic Domain [MBC 235.1] Antibody](https://www.kerafast.com/MediaStorage/Product/Images/Large/909_200120200126269080.jpg "Anti-PECAM-1, Cytoplasmic Domain [MBC 235.1] Antibody")
This IgG1 mouse monoclonal (MBC 235.1) was generated against human PECAM-1 and is specific for the cyotoplasmic domain (aa 697-711) of PECAM-1.
Highlights:
- Reacts with bovine, human and rabbit PECAM-1
- Suitable for Western Blot and Immunohistochemistry applications
Platelet endothelial cell adhesion molecule-1 (PECAM-1) is a 130-kD member of the immunoglobulin superfamily expressed on the surface of circulating platelets, monocytes, neutrophils, and some T cell subsets. It is a major constituent of the endothelial cell intercellular junction where up to a million PECAM-1 molecules are concentrated. With a few minor exceptions, PECAM-1 is not present on fibroblasts, epithelium, muscle or other nonvascular tissue.
From the laboratory of Peter J. Newman, PhD, Blood Center of Wisconsin
Part of The Investigator's Annexe program.
This IgG1 mouse monoclonal (MBC 235.1) was generated against human PECAM-1 and is specific for the cyotoplasmic domain (aa 697-711) of PECAM-1.
Highlights:
- Reacts with bovine, human and rabbit PECAM-1
- Suitable for Western Blot and Immunohistochemistry applications
Platelet endothelial cell adhesion molecule-1 (PECAM-1) is a 130-kD member of the immunoglobulin superfamily expressed on the surface of circulating platelets, monocytes, neutrophils, and some T cell subsets. It is a major constituent of the endothelial cell intercellular junction where up to a million PECAM-1 molecules are concentrated. With a few minor exceptions, PECAM-1 is not present on fibroblasts, epithelium, muscle or other nonvascular tissue.
From the laboratory of Peter J. Newman, PhD, Blood Center of Wisconsin
Part of The Investigator's Annexe program.
| Product Type: | Antibody |
| Antigen: | PECAM-1 |
| Accession ID: | P16284, BC022512 |
| Molecular Weight: | 130 kDa |
| Isotype: | IgG1 |
| Clonality: | Monoclonal |
| Clone Name: | MBC 235.1 |
| Reactivity: | Bovine, human, and rabbit |
| Immunogen: | Cytoplasmic domain peptide AA697-711 |
| Species Immunized: | Mouse |
| Epitope: | Cytoplasmic domain |
| Purification Method: | Protein G |
| Method Used to Determine Concentration: | A280 |
| Buffer: | 10 mM HEPES, 150 mM NaCl |
| Tested Applications: | WB (1ug/mL), IHC (1-5 ug/mL) |
| Concentration: | 2.2 mg/mL |
| Storage: | -20C |
| Shipped: | Cold packs |
| Antibody | Epitope |
| Anti-PECAM-1, IgG Domain 1 [MBC 78.3] | IgG domain 1 |
| Anti-PECAM-1, IgG Domain 5 [MBC 78.1] | IgG domain 5 |
| Anti-PECAM-1, IgG Domain 6 [MBC 78.2] | IgG domain 6 |
| Anti-PECAM-1, Cytoplasmic Domain [MBC 235.1] | Cytoplasmic domain |
- Goldberger A, Middleton KA, Oliver JA, Paddock C, Yan HC, DeLisser HM, Albelda SM, Newman PJ. Biosynthesis and processing of the cell adhesion molecule PECAM-1 includes production of a soluble form. J Biol Chem. 1994 Jun 24;269(25):17183-91.
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