Anti-PECAM-1, Cytoplasmic Domain [MBC 235.1] Antibody

This IgG1 mouse monoclonal (MBC 235.1) was generated against human PECAM-1 and is specific for the cyotoplasmic domain (aa 697-711) of PECAM-1.

Highlights:

  • Reacts with bovine, human and rabbit PECAM-1
  • Suitable for Western Blot and Immunohistochemistry applications

Platelet endothelial cell adhesion molecule-1 (PECAM-1) is a 130-kD member of the immunoglobulin superfamily expressed on the surface of circulating platelets, monocytes, neutrophils, and some T cell subsets. It is a major constituent of the endothelial cell intercellular junction where up to a million PECAM-1 molecules are concentrated. With a few minor exceptions, PECAM-1 is not present on fibroblasts, epithelium, muscle or other nonvascular tissue.

From the laboratory of Peter J. Newman, PhD, Blood Center of Wisconsin

The Investigator's Annexe Part of The Investigator's Annexe program.

Catalog Number Product Size AVAILABILITY Price Qty
EBW004
Anti-PECAM-1, Cytoplasmic Domain [MBC 235.1] Antibody
100ug In stock
Regular Price:$321.00
Specifications

Product Type: Antibody
Antigen: PECAM-1
Accession ID: BC022512
Molecular Weight: 130 kDa
Isotype: IgG1
Clonality: Monoclonal
Clone Name: MBC 235.1
Reactivity: Bovine, human, and rabbit
Immunogen: Cytoplasmic domain peptide AA697-711
Species Immunized: Mouse
Epitope: Cytoplasmic domain
Purification Method: Protein G
Method Used to Determine Concentration: A280
Buffer: 10 mM HEPES, 150 mM NaCl
Tested Applications: WB (1ug/mL), IHC (1-5 ug/mL)
Concentration: 2.2 mg/mL
Storage: -20C
Shipped: Cold packs

Provider
From the laboratory of Peter J. Newman, PhD, Blood Center of Wisconsin
References
  1. Goldberger A, Middleton KA, Oliver JA, Paddock C, Yan HC, DeLisser HM, Albelda SM, Newman PJ. Biosynthesis and processing of the cell adhesion molecule PECAM-1 includes production of a soluble form. J Biol Chem. 1994 Jun 24;269(25):17183-91.

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