This IgG1 mouse monoclonal (MBC 235.1) was generated against human PECAM-1 and is specific for the cyotoplasmic domain (aa 697-711) of PECAM-1.
Platelet endothelial cell adhesion molecule-1 (PECAM-1) is a 130-kD member of the immunoglobulin superfamily expressed on the surface of circulating platelets, monocytes, neutrophils, and some T cell subsets. It is a major constituent of the endothelial cell intercellular junction where up to a million PECAM-1 molecules are concentrated. With a few minor exceptions, PECAM-1 is not present on fibroblasts, epithelium, muscle or other nonvascular tissue.
From the laboratory of Peter J. Newman, PhD, Blood Center of Wisconsin
Part of The Investigator's Annexe program.
|Molecular Weight:||130 kDa|
|Clone Name:||MBC 235.1|
|Reactivity:||Bovine, human, and rabbit|
|Immunogen:||Cytoplasmic domain peptide AA697-711|
|Purification Method:||Protein G|
|Method Used to Determine Concentration:||A280|
|Buffer:||10 mM HEPES, 150 mM NaCl|
|Tested Applications:||WB (1ug/mL), IHC (1-5 ug/mL)|
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