Anti-p120 Catenin [2B12] Antibody

This IgG1 mouse monoclonal antibody [2B12] was generated against tyrosine phosphoproteins purified from chicken embryonic fibroblasts (CEFs) expressing pp60/c-src 527F and 2A/527F and is reactive against chicken, hamster, human, mouse and rat p120/catenin.

Highlights

  • Reacts with chicken, hamster, human, mouse and rat p120/catenin
  • Suitable for Western Blot and Immunoprecipiation applications

Catenins are a family of proteins including found in complexes with cadherin cell adhesion molecules. Specifically, p120 catenin is a member of the Armadillo gene family of junctional plaque proteins. p120 has been shown to play a role in signaling and cancer.

From the laboratories of J. Thomas Parsons, PhD, Sarah (Sally) J. Parsons, PhD, and Albert B. Reynolds, PhD, University of Virginia.

Catalog Number Product Size AVAILABILITY Price Qty
EG2005
Anti-p120 Catenin [2B12] Antibody
100ug 2-3 weeks
Regular Price:$247.00
Specifications

Product Type: Antibody
Antigen: p120/catenin
Molecular Weight: 120 kDa
Isotype: IgG1
Clonality: Monoclonal
Clone Name: 2B12
Reactivity: Chicken, hamster, human, mouse and rat
Immunogen: Tyrosine phosphoproteins purified from chicken embryonic fibroblasts (CEFs) expressing pp60/c-src 527F and 2A/527F
Species Immunized: Mouse
Epitope: AA residues 55-101
Purification Method: Protein G Affinity Chromatography
Buffer: 0.1M Sodium Phosphate, pH 7.4, 0.15M NaCl, 0.05% (w/v) Sodium Azide
Tested Applications: WB, IP
Storage: -20C
Shipped: Cold packs

Provider
From the laboratories of J. Thomas Parsons, PhD, Sarah (Sally) J. Parsons, PhD, and Albert B. Reynolds, PhD, University of Virginia.
References
  1. Kanner SB, Reynolds AB, Parsons JT. Tyrosine phosphorylation of a 120-kilodalton pp60src substrate upon epidermal growth factor and platelet-derived growth factor receptor stimulation and in polyomavirus middle-T-antigen-transformed cells. Mol Cell Biol. 1991 Feb;11(2):713-20.
  2. Kanner SB, Reynolds AB, Vines RR, Parsons JT. Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases.Proc Natl Acad Sci U S A. 1990 May;87(9):3328-32.

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