This IgG2a mouse monoclonal antibody [6G9] was generated against tyrosine phosphoproteins purified from chicken embryonic fibroblasts (CEFs) expressing pp60/c-src 527F and 2A/527F and is reactive against chicken, hamster, human, mouse and rat phospho-tyrosine.
Phosyphorylation is a common modification of proteins that can alter their function, such as protein-protein interaction, protein half- life and cellular localization. Specifically, phosphorylation of tyrosines has been shown to be part of oncogenic transformation, cell cycle and signal transduction during mitogenesis.
Part of The Investigator's Annexe program.
|Reactivity:||Chicken, hamster, human, mouse and rat|
|Immunogen:||Tyrosine phosphoproteins purified from chicken embryonic fibroblasts (CEFs) expressing pp60/c-src 527F and 2A/527F|
|Purification Method:||Protein G Affinity Chromatography|
|Buffer:||0.1M Sodium Phosphate, pH 7.4, 0.15M NaCl, 0.05% (w/v) Sodium Azide|
|Tested Applications:||WB, IP|
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