Anti-Phosphotyrosine [6G9] Antibody

This IgG2a mouse monoclonal antibody [6G9] was generated against tyrosine phosphoproteins purified from chicken embryonic fibroblasts (CEFs) expressing pp60/c-src 527F and 2A/527F and is reactive against chicken, hamster, human, mouse and rat phospho-tyrosine.

Highlights

  • Reacts with chicken, hamster, human, mouse and rat phospho-tyrosine
  • Suitable for Western Blot and Immunoprecipitation applications

Phosyphorylation is a common modification of proteins that can alter their function, such as protein-protein interaction, protein half- life and cellular localization. Specifically, phosphorylation of tyrosines has been shown to be part of oncogenic transformation, cell cycle and signal transduction during mitogenesis.

From the laboratories of J. Thomas Parsons, PhD, Sarah (Sally) J. Parsons, PhD, and Albert B. Reynolds, PhD, University of Virginia.

The Investigator's Annexe Part of The Investigator's Annexe program.

Catalog Number Product Size AVAILABILITY Price Qty
EG2004
Anti-Phosphotyrosine [6G9] Antibody
100ug 2-3 weeks
Regular Price:$323.00
Specifications

Product Type: Antibody
Antigen: Phospho-tyrosine
Isotype: IgG2a
Clonality: Monoclonal
Clone Name: 6G9
Reactivity: Chicken, hamster, human, mouse and rat
Immunogen: Tyrosine phosphoproteins purified from chicken embryonic fibroblasts (CEFs) expressing pp60/c-src 527F and 2A/527F
Species Immunized: Mouse
Purification Method: Protein G Affinity Chromatography
Buffer: 0.1M Sodium Phosphate, pH 7.4, 0.15M NaCl, 0.05% (w/v) Sodium Azide
Tested Applications: WB, IP
Storage: -20C
Shipped: Cold packs

Provider
From the laboratories of J. Thomas Parsons, PhD, Sarah (Sally) J. Parsons, PhD, and Albert B. Reynolds, PhD, University of Virginia.
References
  1. Kanner SB, Reynolds AB, Vines RR, Parsons JT. Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases.Proc Natl Acad Sci U S A. 1990 May;87(9):3328-32.

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