Alkynyl Iodoacetamide

The alkynyl iodoacetamide reacts with nucleophiles, such as cysteine in proteins and peptides. The alkyne moiety allows the compound to be reacted with a fluorescent or biotin label via copper-catalyzed click chemistry for visualization and/or enrichment techniques.

From the laboratory of Ned A. Porter, PhD and Keri A. Tallman, PhD, Vanderbilt University.

The Investigator's Annexe Part of The Investigator's Annexe program.

Catalog Number Product Size AVAILABILITY Price Qty
EVU111
Alkynyl Iodoacetamide
1mg In stock
Regular Price:$205.00
Specifications

Product Type: Small Molecule
Name: Alkynyl iodoacetamide
Chemical Formula: C5H6INO
Source: Synthetic
Molecular Weight: 223.01 kDa
Format: Solid
Solubility: DMSO, EtOH
Storage: -20C
Shipped: Ambient temperature

Provider
From the laboratory of Ned A. Porter, PhD and Keri A. Tallman, PhD, Vanderbilt University.
References
  1. Petrova B, Liu K, Tian C, Kitaoka M, Freinkman E, Yang J, Orr-Weaver TL. Dynamic redox balance directs the oocyte-to-embryo transition via developmentally controlled reactive cysteine changes. Proc Natl Acad Sci U S A. 2018 Aug 6. View Article
  2. Tian C, Sun R, Liu K, Fu L, Liu X, Zhou W, Yang Y, Yang J. Multiplexed Thiol Reactivity Profiling for Target Discovery of Electrophilic Natural Products. Cell Chem Biol. 2017 Nov 16;24(11):1416-1427.e5. View Article

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