Alkynyl 4-hydroxy-2-nonenal (aHNE)

Alkynyl HNE is a surrogate for endogenously generated HNE, a product of lipid oxidation and indicator or oxidative stress.

Highlights:

  • The alkyne moiety allows the compound to be reacted with a fluorescent or biotin label via copper-catalyzed click chemistry for visualization and/or enrichment techniques

From the laboratory of Ned A. Porter, PhD and Keri A. Tallman, PhD, Vanderbilt University.

The Investigator's Annexe Part of The Investigator's Annexe program.

Catalog Number Product Size AVAILABILITY Price Qty
EVU108
Alkynyl 4-hydroxy-2-nonenal (aHNE)
1mg In stock
Regular Price:$308.00
Specifications

Product Type: Small Molecule
Name: Alkynyl 4-hydroxy-2-nonenal (aHNE)
Chemical Formula: C9H12O2
Source: Synthetic
Molecular Weight: 152.19 kDa
Format: Solid
Solubility: DMSO, EtOH
Storage: -20C
Shipped: Ambient temperature

Provider
From the laboratory of Ned A. Porter, PhD and Keri A. Tallman, PhD, Vanderbilt University.
References
  1. Kim, HY. H, Tallman, KA, Liebler, DC, Porter, NA. An Azido-Biotin Reagent for Use in the Isolation of Protein Adducts of Lipid-Derived Electrophiles by Streptavidin Catch and Photo-Release. Mol. Cell. Proteomics 2009, 8, 2080.
  2. Codreanu, SG, Ullery, JC, Zhu, J, Tallman, KA, Beavers, WN, Porter, NA, Marnett, LJ, Zhang, B, Liebler, DC. Alkylation Damage by Lipid Electrophiles Targets Functional Protein Systems. Mol. Cell. Proteomics 2014, 13, 849.
  3. Vila, A, Tallman, KA,Jacobs, AT, Liebler, DC, Porter, NA, Marnett L. Identification of Protein Targets of 4-Hydroxynonenal Using Click Chemistry for ex Vivo Biotinylation of Azido and Alkynyl Derivatives. Chem. Res. Toxicol. 2008, 21, 432.

If you publish research with this product, please let us know so we can cite your paper.

Loading...