Anti-DNA Polymerase Eta [2A10] Antibody

This IgG1 mouse monoclonal (clone 2A10) was generated against the catalytic subunit of human DNA polymerase eta and is specific for human DNA-polymerase Eta (Pol η).

Highlights:

  • Specific for human DNA-polymerase Eta (Pol η)
  • This antibody doesn't interfere with substrate binding (DNA).
  • Recommended for WB, IP, and ELISA applications

DNA polymerase eta (Pol η) is a protein in humans encoded by the POLH gene, and is particularly important for allowing accurate translesion synthesis of DNA damage resulting from ultraviolet (UV) radiation. Mutations in the POLH gene can result in Xeroderma Pigmentosum (XP), an autosomonal recessive genetic disorder where the inherited are extremely sensitive to UV rays from sunlight.

From the laboratory of Aneel K. Aggarwal, PhD, Icahn School Of Medicine at Mount Sinai.

Catalog Number Product Size AVAILABILITY Price Qty
EMS502
Anti-DNA Polymerase Eta [2A10] Antibody
100ug 2-3 weeks
Regular Price:$385.00
Specifications

Product Type: Antibody
Antigen: POLH, RAD30
Accession ID: AY388614.1
Molecular Weight: 47.5 kDa
Isotype: IgG1
Clonality: Monoclonal
Clone Name: 2A10
Reactivity: Human
Immunogen: Catalytic core of enzyme (amino acids 1-430)
Species Immunized: Mouse
Buffer: 0.1M Sodium Phosphate, pH 7.4, 0.15M NaCl, 0.05% (w/v) Sodium Azide
Tested Applications: ELISA, WB and IP
Storage: -20C
Shipped: Cold packs

Provider
From the laboratory of Aneel K. Aggarwal, PhD, Icahn School Of Medicine at Mount Sinai.
References

If you publish research with this product, please let us know so we can cite your paper.

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