Anti-GRIM-19 [1A8] Antibody

This IgG2a mouse monoclonal (clone 1A8) was generated against recombinant human Gene associated with Retinoid - Interferon-induced Mortality 19 (GRIM-19), and recognizes human and mouse GRIM-19.

Highlights:

  • Recognizes human and mouse GRIM-19
  • Recommended for WB, IP, IHC, IF, and ELISA applications

GRIM-19, otherwise known as designated cell death-regulatory protein GRIM 19 and NADH dehydrogenase ubiquinone 1 alpha subcomplex subunit 13, is known to play a role in programmed cell death (apoptosis) and the electron transport chain. GRIM19 is widely expressed within tissues, including heart, skeletal muscle, liver, kidney and placenta. Mutations in GRIM-19 have been associated with Hurthle cell thyroid carcinoma (HCTC), a rare type of thyroid cancer.

From the laboratory of Dhan V. Kalvakolanu, PhD, University of Maryland, Baltimore.

The Investigator's Annexe Part of The Investigator's Annexe program.

Catalog Number Product Size AVAILABILITY Price Qty
EMD201
Anti-GRIM-19 [1A8] Antibody
100ug 2-3 weeks
Regular Price:$256.00
Specifications

Product Type: Antibody
Accession ID: 51079
Antigen: Gene associated with Retinoid - Interferon-induced Mortality 19 (GRIM-19)
Molecular Weight: 16 kDa
Isotype: IgG2a
Clonality: Monoclonal
Clone Name: 1A8
Reactivity: Human and mouse
Immunogen: Recombinant human GRIM-19
Species Immunized: Mouse
Buffer: 0.1M Sodium Phosphate, pH 7.4, 0.15M NaCl, 0.05% (w/v) Sodium Azide
Tested Applications: WB, IP (1:200), IHC, IF (1:1000), ELISA (1:200,000)
Storage: -20C
Shipped: Cold packs

Provider
From the laboratory of Dhan V. Kalvakolanu, PhD, University of Maryland, Baltimore.
References
  1. Hu J, Angell JE, Zhang J, Ma X, Seo T, Raha A, Hayashi J, Choe J, Kalvakolanu DV. Characterization of monoclonal antibodies against GRIM-19, a novel IFN-beta and retinoic acid-activated regulator of cell death. J. Interferon Cytokine Res. 2002 Nov;22(11):1150.

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