This IgG2a mouse monoclonal (clone 1A8) was generated against recombinant human Gene associated with Retinoid - Interferon-induced Mortality 19 (GRIM-19), and recognizes human and mouse GRIM-19.
GRIM-19, otherwise known as designated cell death-regulatory protein GRIM 19 and NADH dehydrogenase ubiquinone 1 alpha subcomplex subunit 13, is known to play a role in programmed cell death (apoptosis) and the electron transport chain. GRIM19 is widely expressed within tissues, including heart, skeletal muscle, liver, kidney and placenta. Mutations in GRIM-19 have been associated with Hurthle cell thyroid carcinoma (HCTC), a rare type of thyroid cancer.
From the laboratory of Dhan V. Kalvakolanu, PhD, University of Maryland, Baltimore.
Part of The Investigator's Annexe program.
|Antigen:||Gene associated with Retinoid - Interferon-induced Mortality 19 (GRIM-19)|
|Molecular Weight:||16 kDa|
|Reactivity:||Human and mouse|
|Immunogen:||Recombinant human GRIM-19|
|Buffer:||PBS, 0.05% (w/v) Sodium Azide|
|Tested Applications:||WB, IP (1:200), IHC, IF (1:1000), ELISA (1:200,000)|
If you publish research with this product, please let us know so we can cite your paper.