This IgG monoclonal antibody was generated against carboxy-methyl lysine (CML)-modified keyhole limpet hemocyanin (KLH), and is reactive against human, mouse and rat CML.
Carboxy-methyl lysine (CML) otherwise known as N(epsilon)-(carboxymethyl) lysine, is an advanced glycation end product (AGE) found on proteins and lipids as a result of oxidative stress and chemical glycation. AGEs are formed both outside and inside the body. They are substances that can be a factor in the development or worsening of many degenerative diseases including Diabetes and Alzheimer's disease. CML is the most widely used marker for AGEs in food analysis.
From the laboratory of Helen Vlassara, MD, Icahn School of Medicine at Mount Sinai
Part of The Investigator's Annexe program.
|Name:||Anti-Advanced Glycation End products (AGE), Carboxy-Methyl Lysine (CML) - AGE-CML [6C7] Antibody|
|Reactivity:||Human, Mouse, Rat|
|Purification Method:||Protein G Affinity Chromatography|
|Buffer:||0.1M Sodium Phosphate, pH 7.4, 0.15M NaCl, 0.05% (w/v) Sodium Azide|
|Tested Applications:||WB (1:5000-8000), IHC (1:50-100), ELISA (1:6000)|
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