Anti-SARS-CoV Spike Protein [S391] Antibody

This mouse IgG1 monoclonal antibody was generated against SARS-CoV Spike Protein and recognizes SARS virus infected samples.

Highlights:

  • Reacts with samples infected with SARS virus
  • No binding detected towards SARS-CoV-2 spike protein domains S1/S2. Please see: PDF ELISA Results
  • Suitable for Western blot and ELISA applications

It has recently been shown that SARS (severe acute respiratory syndrome) is caused by a human coronavirus. Coronaviruses are a major cause of upper respiratory diseases in humans. The genomes of these viruses are positive stranded RNA approximately 27 to 31kb in length. SARS infection can be mediated by the binding of the viral spike protein, a glycosylated 139 kDa protein and the major surface antigen of the virus, to the angiotensin converting enzyme 2 (ACE2) on target cells.

From the laboratory of John W. Kappler, PhD and Philippa Marrack, PhD, National Jewish Health.

Catalog Number Product Size AVAILABILITY Price Qty
ENJ002
Anti-SARS-CoV Spike Protein [S391] Antibody
100ug In stock
Regular Price:$385.00
Specifications

Product Type: Antibody
Accession ID: AAP41037
Antigen: SARS-CoV spike protein
Molecular Weight: 180 kDa
Isotype: IgG1
Clonality: Monoclonal
Clone Name: S391
Reactivity: Reacts with samples infected with SARS virus
Immunogen: Full length SARS-CoV spike protein expressed in HEK293 cell line (Preparation is described in Cell Res. 2008 Feb;18(2):290-301.)
Species Immunized: Balb/c mouse
Purification Method: Protein G column
Buffer: 0.1M Sodium Phosphate, pH 7.4, 0.15M NaCl, 0.05% (w/v) Sodium Azide
Tested Applications: WB, ELISA
Storage: -20C
Shipped: Cold packs

Data
This antibody was tested via ELISA for reactivity towards SARS-CoV-2 spike protein domains S1/S2. No binding was observed at the concentrations tested. Please see: PDF ELISA Results.
Provider
From the laboratory of John W. Kappler, PhD and Philippa Marrack, PhD, National Jewish Health.
References

If you publish research with this product, please let us know so we can cite your paper.

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