Anti-ADAM15 (human), Extracellular Domain Antibody

This rabbit IgG polyclonal antibody was generated against an extracellular domain fusion protein of human ADAM15 with an IgG Fc domain and is specific for the extracellular domain of human ADAM15.

The ADAM (A Disintegrin And Metalloprotease Domain) family is a unique group of proteins that has the ability to cleave or shed extracellular portions of transmembrane proteins. In addition, ADAMs are involved in cell-cell and cell-matrix interactions (e.g., fertilization, muscle development and neurogenesis).

ADAM15 (Metargidin) is a membrane-anchored glycoprotein that has been implicated in pathological neovascularization and prostate cancer metastasis.

From the laboratory of Carl P. Blobel, MD, PhD, Hospital for Special Surgery.

The Investigator's Annexe Part of The Investigator's Annexe program.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
Anti-ADAM15 (human), Extracellular Domain Antibody
100uL In stock
Regular Price:$345.00
On Sale:

Product Type: Antibody
Antigen: ADAM15 Extracellular Domain with IgG Fc Domain
Accession ID: Q13444
Molecular Weight: ~100 kDa
Isotype: IgG
Clonality: Polyclonal
Reactivity: Human
Immunogen: Extracellular Domain fusion protein of human ADAM15 with an IgG Fc Domain
Species Immunized: Rabbit
Epitope: Extracellular domain
Purification Method: Serum, not purified
Tested Applications: Western blot, only works on non-reduced samples (no DTT or BME) 1:500
Storage: -80C
Shipped: Dry ice

Antibody Species Reactivity Specificity
ADAM9 Human Cytoplasmic Domain
ADAM9 Mouse Cytoplasmic Domain
ADAM12 Mouse Cytoplasmic Domain
ADAM15 Human Cytoplasmic Domain
ADAM15 Mouse Cytoplasmic Domain
ADAM15 Human Extracellular Domain
ADAM15 Mouse Disintegrin Domain
ADAM17 Mouse Cytoplasmic Domain
ADAM17 Mouse Pro domain
ADAM19 Mouse Cytoplasmic Domain
ADAM28 Mouse Cytoplasmic Domain
ADAM28 Mouse Extracellular Domain
SNX9 Mouse Cytoplasmic Domain
From the laboratory of Carl P. Blobel, MD, PhD, Hospital for Special Surgery.
  1. Krätzschmar, J.; Lum, L.; Blobel, C. P. Metargidin, a membrane-anchored metalloprotease-disintegrin protein with an RGD integrin binding sequence. J. Biol. Chem. 1996, 271, 4593-4596.
  2. Horiuchi, K.; Weskamp, G.; Lum, L.; Hammes, H. P.; Cai, H.; Brodie, T. A.; Ludwig, T.; Chiusaroli, R.; Baron, R.; Preissner, K. T.; Manova, K.; Blobel, C. P. Potential role for ADAM15 in pathological neovascularization in mice. Mol. Cell. Biol. 2003, 23, 5614-5624.

If you publish research with this product, please let us know so we can cite your paper.