This monoclonal antibody was generated against a recombinant MUC18 (D1-D5) Fc chimeric protein and recognizes human MUC18.
MUC18 (also known as CD146, melanoma cell adhesion molecule or MCAM) is a cell adhesion molecule that belongs to the immunoglobulin superfamily and is used as a marker for endothelial cell lineage. MUC18 is overexpressed in certain lesions such as melanoma, where increased expression has been shown to correlate inversely with patient prognosis.
From a laboratory at Cancer Research Technology, Cancer Research Technology.
Part of The Investigator's Annexe program.
|Antigen:||MUC18 (CD146, MCAM)|
|Molecular Weight:||~113 kDa|
|Immunogen:||Recombinant MUC18 (D1-D5) Fc chimeric protein|
|Purification Method:||Protein G|
|Buffer:||0.1M Sodium Phosphate, pH 7.4, 0.15M NaCl, 0.05% (w/v) Sodium Azide|
|Tested Applications:||FACS, IHC, IHC-Frozen|
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