Anti-Beta Tubulin [AA2] Antibody
This IgG1 mouse antibody was generated against bovine brain tubulin (amino acids 416-431) and recognizes mammalian homologs of beta tubulin types I, II, III, IV.
Microtubules are required for many well characterized functions in eukaryotic cells, including the movement of chromosomes in mitosis and meiosis, intracellular transport, establishment and maintenance of cellular morphology, cell growth, cell migration and morphogenesis in multicellular organisms. The building block of a microtubule is the tubulin subunit, a heterodimer of alpha and beta tubulin. Both of these monomers are found in all eukaryotes, and their sequences are highly conserved. The tubulin protein is a major target of drug molecules, and consequently, tubulin inhibitors have attracted great attention as antimitotic antitumor agents for chemotherapeutic use.
From the laboratories of Anthony Frankfurter, PhD and Anthony Spano, PhD, University of Virginia.
This IgG1 mouse antibody was generated against bovine brain tubulin (amino acids 416-431) and recognizes mammalian homologs of beta tubulin types I, II, III, IV.
Microtubules are required for many well characterized functions in eukaryotic cells, including the movement of chromosomes in mitosis and meiosis, intracellular transport, establishment and maintenance of cellular morphology, cell growth, cell migration and morphogenesis in multicellular organisms. The building block of a microtubule is the tubulin subunit, a heterodimer of alpha and beta tubulin. Both of these monomers are found in all eukaryotes, and their sequences are highly conserved. The tubulin protein is a major target of drug molecules, and consequently, tubulin inhibitors have attracted great attention as antimitotic antitumor agents for chemotherapeutic use.
From the laboratories of Anthony Frankfurter, PhD and Anthony Spano, PhD, University of Virginia.
| Product Type: | Antibody |
| Name: | Anti-Beta Tubulin; clone AA2 |
| Accession ID: | P07437 |
| Host: | balb/c mouse |
| Isotype: | IgG1 |
| Clonality: | Monoclonal |
| Clone Name: | AA2 |
| Specificity: | Beta Tubulin (all mammalian homologs) |
| Immunogen: | Generated against bovine brain tubulin (amino acids 416-431) |
| Format: | Liquid |
| Purification Method: | Protein G affinity purified |
| Buffer: | PBS, 0.05% (w/v) Sodium Azide |
| Tested Applications: | WB, IHC, IP, IF |
| Concentration: | 1mg/mL |
| Amount: | 100uL |
| Storage: | Store at 4C |
| Shipped: | Cold packs |
- Moody SA, Miller V, Spanos A, Frankfurter A. Developmental expression of a neuron-specific beta-tubulin in frog (Xenopus laevis): a marker for growing axons during the embryonic period. J Comp Neurol. 8;364(2):219-230, (1996).
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