Anti-Beta Tubulin [AA2] Antibody

This IgG1 mouse antibody was generated against bovine brain tubulin (amino acids 416-431) and recognizes mammalian homologs of beta tubulin types I, II, III, IV.

Microtubules are required for many well characterized functions in eukaryotic cells, including the movement of chromosomes in mitosis and meiosis, intracellular transport, establishment and maintenance of cellular morphology, cell growth, cell migration and morphogenesis in multicellular organisms. The building block of a microtubule is the tubulin subunit, a heterodimer of alpha and beta tubulin. Both of these monomers are found in all eukaryotes, and their sequences are highly conserved. The tubulin protein is a major target of drug molecules, and consequently, tubulin inhibitors have attracted great attention as antimitotic antitumor agents for chemotherapeutic use.

From the laboratories of Anthony Frankfurter, PhD and Anthony Spano, PhD, University of Virginia.

The Investigator's AnnexePart of The Investigator's Annexe program.

Catalog Number Product Size AVAILABILITY Price Qty
EG0035
Anti-Beta Tubulin [AA2] Antibody
100ug 2-3 weeks
Regular Price:$328.00
Specifications

Product Type: Antibody
Name: Anti-Beta Tubulin; clone AA2
Host: balb/c mouse
Isotype: IgG1
Clonality: Monoclonal
Clone Name: AA2
Specificity: Beta Tubulin (all mammalian homologs)
Immunogen: Generated against bovine brain tubulin (amino acids 416-431)
Format: Liquid
Purity: Protein G affinity purified
Tested Applications: WB, IHC, IP, IF
Concentration: 1mg/mL
Amount: 100uL
Storage: Store at 4C
Shipped: Cold packs

Provider
From the laboratories of Anthony Frankfurter, PhD and Anthony Spano, PhD, University of Virginia.
References
  1. Moody SA, Miller V, Spanos A, Frankfurter A. Developmental expression of a neuron-specific beta-tubulin in frog (Xenopus laevis): a marker for growing axons during the embryonic period. J Comp Neurol. 8;364(2):219-230, (1996).

If you publish research with this product, please let us know so we can cite your paper.

Loading...