Anti-CD18 [C71/16] Hybridoma
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CD18, also known as integrin beta-2, is a member of the leukocyte integrin family of heterodimeric adhesion molecules. Integrins are cell surface proteins composed of an alpha subunit and a beta subunit that participate in cell adhesion and cell surface mediated signalling. CD18 combines with alpha subunits, CD11a, CD11b, and CD11c, to form LFA-1, Mac-1 and gp150/95. CD18 is believed to play an immportant role in the immune response and defects in this gene cause leukocyte adhesion deficiency.
CD18, also known as integrin beta-2, is a member of the leukocyte integrin family of heterodimeric adhesion molecules. Integrins are cell surface proteins composed of an alpha subunit and a beta subunit that participate in cell adhesion and cell surface mediated signalling. CD18 combines with alpha subunits, CD11a, CD11b, and CD11c, to form LFA-1, Mac-1 and gp150/95. CD18 is believed to play an immportant role in the immune response and defects in this gene cause leukocyte adhesion deficiency.
Specifications
| Product Type: | Antibody |
| Name: | Anti-CD18 [C71/16] Hybridoma |
| Cell Type: | Hybridoma Cell Line |
| Antigen: | CD18 |
| Isotype: | IgG |
| Clonality: | Monoclonal |
| Clone Name: | C71/16 |
| Reactivity: | Mouse |
| Specificity: | CD18 |
| Immunogen: | Cell membrane glycoproteins derived from BW5147 |
| Growth Conditions: | Dulbecco's Modified Eagles medium (DMEM) + 10% fetal bovine serum (FBS) + non-essential amino acid + sodium pyruvate + 50uM beta-mercaptoethanol |
| Cryopreservation: | Resuspend cells in DMEM, 20% FBS, and 10% DMSO. Store in liquid nitrogen. |
| Species Immunized: | Rat |
| Storage: | Liquid Nitrogen |
| Shipped: | Dry Ice |
References
- J. Exp. Med. (1981) 154:1517-1524
- Blood (2008) 111:3607-14
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