Anti-CD45 [T29/33.6.1] Hybridoma
![Anti-CD45 [T29/33.6.1] Hybridoma](https://www.kerafast.com/MediaStorage/Product/Images/Large/3570_2001202001281435690.jpg "Anti-CD45 [T29/33.6.1] Hybridoma")
This hybridoma line produces a mouse anti-human CD45 monoclonal antibody (T29/33.6.1).
CD45 is a type 1 transmembrane protein tyrosine phosphatase expressed by all haematopoietic stem cells except erythrocytes and platelets. CD45 is needed for the activation and suppression of T cells after interacting with antigen-presenting cells. CD45 regulates T cell activation by gatekeeping antigen presentation and filtering based on binding strength.
This hybridoma line produces a mouse anti-human CD45 monoclonal antibody (T29/33.6.1).
CD45 is a type 1 transmembrane protein tyrosine phosphatase expressed by all haematopoietic stem cells except erythrocytes and platelets. CD45 is needed for the activation and suppression of T cells after interacting with antigen-presenting cells. CD45 regulates T cell activation by gatekeeping antigen presentation and filtering based on binding strength.
Specifications
| Product Type: | Antibody |
| Name: | Anti-CD45 [T29/33.6.1] Hybridoma |
| Cell Type: | Hybridoma cell line |
| Antigen: | CD45 |
| Isotype: | IgG1 |
| Clonality: | Monoclonal |
| Clone Name: | T29/33.6.1 |
| Reactivity: | Human |
| Specificity: | CD45 |
| Immunogen: | Human Cell Line CCRF-CEM |
| Growth Conditions: | Dulbecco’s Modified Eagle medium (DMEM) + 10% fetal bovine serum (FBS) + non-essential amino acid + sodium pyruvate + 50uM beta-mercaptoethanol |
| Cryopreservation: | Resuspend cells in DMEM, 20% FBS, and 10% DMSO. Store in liquid nitrogen. |
| Species Immunized: | Mouse |
| Tested Applications: | Immunoprecipitation, Indirect Immunofluorescence |
| Storage: | Liquid Nitrogen |
| Shipped: | Dry Ice |
References
- Human homologue of murine T200 glycoprotein. Omary M.B., Trowbridge I.S., Battifora H.A. J. Exp. Med. (1980) 152:842-852
- Arthritis Rheum (2007) 56: 291-302.
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