Anti-Cortactin [4F11] Antibody

This mouse IgG1 monoclonal antibody was generated against a mixture of affinity-purified tyrosine phosphoproteins from chick embryo fibroblasts expressing activated pp60src, and recognizes Cortactin (CTTN).

Highlights:

  • Reacts with 80 kDa and 85 kDa CTTN in avian cells, and 80 kDa protein in rodent and human cells
  • Suitable for Western Blot, Immunoprecipitation, Immunofluorescence and Immunohistochemistry applications

Cortactin (CTTN) is a thin, elongated monomeric protein located in the cytoplasm. It contributes to the organization of the actin cytoskeleton and cell shape. CTTN is important promoting lamellipodia formation, invadopodia formation, cell migration, and endocytosis. It is overexpressed in breast cancer and squamous cell carcinomas of the head and neck.

From a laboratory at University of Virginia.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
EG1052
Anti-Cortactin [4F11] Antibody
100ug 4-6 weeks
Regular Price:$299.00
On Sale:
Specifications

Product Type: Antibody
Name: Anti-Cortactin [4F11] Antibody
Antigen: Cortactin
Molecular Weight: 62kDa
Isotype: IgG1
Clonality: Monoclonal
Clone Name: 4F11
Reactivity: Avian, rat, mouse, human, bovine & hamster Cortactin
Specificity: Recognizes 80 kDa and 85 kDa CTTN in avian cells, and 80 kDa protein in rodent and human cells
Immunogen: Tyrosine phosphoproteins purified from chick embryo fibroblasts expressing activated pp60src
Species Immunized: Mouse
Purification Method: Protein A or A/G affinity purified
Buffer: PBS, 0.05% Sodium Azide
Tested Applications: WB, IP, IF, IHC
Storage: -20C
Shipped: Cold packs

Provider
From a laboratory at University of Virginia.
References
  1. Kanner SB, Reynolds AB, Vines RR, Parsons JT. Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases. Proc Natl Acad Sci U S A. 1990 May;87(9):3328-32. doi: 10.1073/pnas.87.9.3328. PMID: 2110361; PMCID: PMC53893.

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