Anti-Nuclear Transport Factor 2 [4F5] Antibody

This mouse IgG2b monocloncal antibody was generated against human Nuclear transport factor 2 (NTF2) and recognizes both human and xenopus NTF2 homologs.

Highlights:

  • Reacts with both human and xenopus NTF2 homologs
  • Suitable for Western Blot and Immunofluorescence applications

Nucleocytoplasmic transport plays an important role in the regulation of diverse cellular processes, including transcription and translation, growth factor-mediated signaling, stress responses, and cell cycle control. Nuclear transport factor 2 (NTF2) is a soluble transport protein originally identified by its ability to stimulate nuclear localization signal (NLS)-dependent protein import in digitonin-permeabilized cells. NTF2 has been shown to bind nuclear pore complex proteins and the GDP form of Ran in vitro.

From the laboratory of Bryce M. Paschal, PhD, University of Virginia.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
EG1055
Anti-Nuclear Transport Factor 2 [4F5] Antibody
100ug 4-6 weeks
Regular Price:$328.00
On Sale:
Specifications

Product Type: Antibody
Name: Anti-Nuclear Transport Factor 2 [4F5] Antibody
Antigen: Nuclear transport factor 2
Accession ID: Q9UKK6
Molecular Weight: 14kDa
Isotype: IgG2b
Clonality: Monoclonal
Clone Name: 4F5
Reactivity: Human, mouse, rat, human, monkey, hamster, chicken,xenopus
Immunogen: Recombinant human NTF2
Species Immunized: Mouse
Epitope: Amino acids 82-169
Purification Method: Protein A or A/G affinity purified
Buffer: PBS, 0.05% Sodium Azide
Tested Applications: WB, IF
Storage: -20C
Shipped: Cold packs

Provider
From the laboratory of Bryce M. Paschal, PhD, University of Virginia.
References
  1. Steggerda SM, Black BE, Paschal BM. Monoclonal antibodies to NTF2 inhibit nuclear protein import by preventing nuclear translocation of the GTPase Ran. Mol Biol Cell. 2000 Feb;11(2):703-19. doi: 10.1091/mbc.11.2.703. PMID: 10679025; PMCID: PMC14804.

If you publish research with this product, please let us know so we can cite your paper.

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