Anti-Adenosine Receptor A2a [7F6-G5-A2] Antibody

This IgG2a mouse antibody was generated against human adenosine A2a receptor and recognizes the 3rd intracellular loop of human, mouse, rabbit, dog, and rat A2a homologs.

Highlights:

  • Reacts with 3rd intracellular loop of human, mouse, rabbit, dog, and rat A2AR homologs
  • Suitable for Western Blot, Immunohystochemistry and Flow Cytometry applications

The A2A adenosine receptor, also known as ADORA2A, is an adenosine receptor (one of its several receptor subtypes) that is a member of the G protein-coupled receptor (GPCR) family. Its activity is mediated by G proteins which activate adenylyl cyclase. A2A receptor is commonly found in basal ganglia, vasculature, T lymphocytes, and platelets. It is thought to protect against tissue inflammation through its ability to suppress the immune cells, and may play a role in myocardial oxygen demand regulation and increase of coronary circulation by vasodilation. Because its expression is also found in the brain, it may be an attractive target for research studies or treatments of insomnia, pain, depression, and Parkinson's disease.

From a laboratory at University of Virginia.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
EG1048
Anti-Adenosine Receptor A2a [7F6-G5-A2] Antibody
100ug 4-6 weeks
Regular Price:$328.00
On Sale:
Specifications

Product Type: Antibody
Name: Anti-Adenosine Receptor A2a [7F6-G5-A2] Antibody
Antigen: Adenosine Receptor A2a
Accession ID: P29274
Molecular Weight: 43kDa
Isotype: IgG2a
Clonality: Monoclonal
Clone Name: 7F6-G5-A2
Reactivity: Rabbit, canine, human, mouse, rat, dog
Immunogen: 6His-tagged full length human recombinant A2A receptor
Species Immunized: Mouse
Buffer: PBS, 0.05% Sodium Azide
Tested Applications: WB, IHC, FC
Storage: -20C
Shipped: Cold packs

Provider
From a laboratory at University of Virginia.
References
  1. Koshiba M, Rosin DL, Hayashi N, Linden J, Sitkovsky MV. Patterns of A2A extracellular adenosine receptor expression in different functional subsets of human peripheral T cells. Flow cytometry studies with anti-A2A receptor monoclonal antibodies. Mol Pharmacol. 1999 Mar;55(3):614-24. PMID: 10051547.

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