mCh-Moonbody Plasmid

mCh-Moonbody Plasmid for expression of GFP-tagged light switchable monobody against the SH2 domain of ABL kinase (Light-OFF switch).


  • Can be controlled by photons (light) emitting in the range of 400-500nm
  • Substantially smaller in size than conventional antibodies
  • Responds to light within seconds in the form of OFF-switches

Intracellular single-domain antibodies (intrabodies) and their mimetics derived from synthetic protein scaffolds (e.g., nanobodies and monobodies) are used with the aim to overcome shortcomings of natural antibody molecules. Due to their smaller size, no disulfide-bond formation and ease of in vitro and cellular expression, monobodies may serve as useful tools for both research and potential diagnostic/therapeutic applications. Several classes of chemically or light-dependent single-domain antibodies have been produced through recent engineering efforts.

From the laboratory of Yubin Zhou, MD, PhD, Texas A&M University.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
mCh-Moonbody Plasmid
250ng In stock
Regular Price:$80.00
On Sale:

Product Type: Plasmid
Gene/insert name: mCh-Moonbody
Organism: Synthetic
Antibiotic Resistance: Amp
Fusion Tag(s): mCherry
Grow in E. coli at 37 C: Yes
Cloning Site 5': NheI
Cloning Site 3': XbaI
Insert Size: 1464bp
Vector Backbone and Size: pcDNA3.1, 5338bp
High or low copy: High
Storage: -20C
Shipped: Room temperature

From the laboratory of Yubin Zhou, MD, PhD, Texas A&M University.
  1. He L, Tan P, Huang Y, Zhou Y. Design of Smart Antibody Mimetics with Photosensitive Switches. Adv Biol (Weinh). 2021 May;5(5):e2000541. doi: 10.1002/adbi.202000541. Epub 2021 Feb 5. PMID: 34028213; PMCID: PMC8295464.

If you publish research with this product, please let us know so we can cite your paper.