Macrophage cell line isolated from bone marrow in B6/129 mice after immortalization with a retrovirus (J2) containing the myc and v-raf oncogenes.
B6/129 mouse line is a cross between C57BL/6 females (B6) and 129P3 males (129P). Potential uses for these mice include hybrid vigor, as a background for deleterious mutations, to create or enhance expression of polygenic diseases, to determine the mode of inheritance, to provide physiological buffering (present a broader array of responses to various stresses) and as approximate controls for some genetically engineered strains.
From the laboratory of Howard A. Young, PhD, National Cancer Institute/NIH.
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|Product Type:||Cell Line|
|Growth Conditions:||DMEM + 10% FBS + Glutamine|
|Cryopreservation:||90% FBS + 10% DMSO|
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