Neutrophil Specific, PET Imaging Agent

This neutrophil-detection reagent, cFLFLFK-PEG-64Cu, targets the formyl peptide receptor (FPR) on leukocytes and is suitable for PET imaging applications.

Highlights:

  • Copper-64 labeled PET imaging agent specific for neutrophils
  • Consists of neutrophil-specific cFLFLF; biocompatible PEG; and the radioisotope 64Cu
  • Can be used for in vivo imaging and in vitro cell function assays
  • Probe has the ability to detect and quantify neutrophilic accumulation

Neutrophils are among the first leukocytes to reach a site of injury, and they are abundant at focal sites of infection. The ability to detect and quantify neutrophilic accumulatio could be important not only in locating and identifying inflammatory lesions but also in facilitating the development and testing of antiinflammatory agents.

From the laboratory of Dongfeng Pan, PhD, University of Virginia.

Catalog Number Product Size AVAILABILITY Price Qty
EG0046
Neutrophil Specific, PET Imaging Agent
200ug 1-2 weeks
Regular Price:$200.00
Specifications

Product Type: Small Molecule
Name: cFLFLF-PEG-NH2
Molecular Weight: ~4.4 kDa
Format: White crystal
Purity: 95%
Tested Applications: In vitro and in vivo applications
Solubility: Acetonitrile, ethanol, water
Spectral Information: Mass spectrometry
Storage: 4C
Shipped: Room Temperature

Data
PET Neutrophil Imaging Agent
Provider
From the laboratory of Dongfeng Pan, PhD, University of Virginia.
References
  1. Zhang Y, Kundu B, Fairchild KD, et al. Synthesis of novel neutrophil-specific imaging agents for Positron Emission Tomography (PET) imaging. Bioorg Med Chem Lett. 2007;17(24):6876-6878.
  2. Locke LW, Chordia MD, Zhang Y, et al. A novel neutrophil-specific PET imaging agent: cFLFLFK-PEG-64Cu. J Nucl Med. 2009;50(5):790-797.

If you publish research with this product, please let us know so we can cite your paper.

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