Human prostate cancer cell line, 22Rv1-undup1 is one of the clones isolated from 22Rv1 that is genetically corrected using TAL effector nuclease to delete the tandem duplication of 2b-exon3-CE1-3 of androgen receptor genome in 22Rv1 cell that drives the expression of androgen receptor variant 7 (ARv7).
Prostate cancer is the development of cancer in the prostate, a gland in the male reproductive system. The androgen receptor (AR) helps prostate cancer cells to survive and is a target for many anti cancer research studies by looking at inhibition.
From the laboratory of Scott S. Dehm, PhD, University of Minnesota, Twin Cities.
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|Product Type:||Cell Line|
|Cell Type:||Prostate Cancer|
|Biosafety Level:||BSL 2|
|Growth Conditions:||RPMI Medium 1640 - L-Glutamine (Invitrogen 11875), 10% FBS, 1xPen/Strep|
|Subculturing:||Seed 22Rv1-undup1 cell at 1X106/T75 flask, change medium twice a week and split 1 to 4 splitting once to twice a week|
|Cryopreservation:||RPMI1640 , 20 % FBS and 10 %DMSO|
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