22-Hydroxycholesterol-26-al transaminase (GABAT1)
GABAT1 aminotransferase enzyme from Veratrum californicum that is able to transfer an amino group from Γ-aminobutyric acid to the compound 22-Hydroxycholesterol-26[25(S)]-al to form 22(R)-Hydroxy-26[25(S)]-aminocholesterol. This enzyme functions in steroid alkaloid biosynthesis.
From the laboratory of Toni M. Kutchan, PhD, and Megan Augustin, Donald Danforth Plant Science Center.
GABAT1 aminotransferase enzyme from Veratrum californicum that is able to transfer an amino group from Γ-aminobutyric acid to the compound 22-Hydroxycholesterol-26[25(S)]-al to form 22(R)-Hydroxy-26[25(S)]-aminocholesterol. This enzyme functions in steroid alkaloid biosynthesis.
From the laboratory of Toni M. Kutchan, PhD, and Megan Augustin, Donald Danforth Plant Science Center.
Specifications
| Product Type: | Protein |
| Name: | 22-Hydroxycholesterol-26-al transaminase (GABAT1) |
| Accession ID: | KJ869262 |
| Source: | Sf9 Cells |
| Molecular Weight: | 53,962 |
| Buffer: | 100 mM tricine pH 7.5/ 5 mM thioglycolic acid |
| Comments: | Requires pyridoxal-5-phosphate and Γ-aminobutyric acid |
| Storage: | -80C |
| Shipped: | Dry Ice |
Provider
From the laboratory of Toni M. Kutchan, PhD, and Megan Augustin, Donald Danforth Plant Science Center.
References
- Augustin MM, Ruzicka DR, Shukla AK, et al. Elucidating steroid alkaloid biosynthesis in Veratrum californicum: production of verazine in Sf9 cells. Plant J. 2015;82(6):991-1003.
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