Anti-c-Myc [9E11] Antibody

This mouse IgG2a monoclonal antibody recognizes human c-Myc and was generated against a synthetic peptide corresponding to residues 408-420 of human c-Myc.

The c-Myc and N-Myc oncogenes are members of the Myc family of transcription factors that regulate cell proliferation and apoptosis. c-Myc is expressed in proliferating tissues and increased c-Myc expression is found in many cancers. N-Myc is amplified in a proportion of neuroblastoma patients. Myc (c-Myc) is a regulator gene that codes for a transcription factor is believed to regulate expression of 15% of all genes. Mutated c-myc leads to the unregulated expression of many genes, some of which are involved in cell proliferation and results in the formation of cancer.

From a laboratory at Cancer Research Technology.

The Investigator's Annexe Part of The Investigator's Annexe program.

Catalog Number Product Size AVAILABILITY Price Qty
EW0004
Anti-c-Myc [9E11] Antibody
0.1mg (100uL at 1mg/mL) 2-3 weeks
Regular Price:$356.00
Specifications

Product Type: Antibody
Name: Anti c-Myc (9E11) monoclonal antibody
Host: Balb/c
Isotype: IgG2a
Clonality: Monoclonal
Clone Name: 9 E11
Specificity: Human
Immunogen: Residues 408-420. AEEQKLISEEDL.
Format: Liquid
Purity: Protein G purified
Tested Applications: Frozen, Immunoprecipitation, Paraffin embedded
Concentration: 1mg/mL
Amount: 100uL
Storage: Store at 4C
Shipped: Cold packs

Provider
From a laboratory at Cancer Research Technology.
References
  1. Halme A, Bumgarner S, Styles C, Fink GR. Genetic and epigenetic regulation of the FLO gene family generates cell-surface variation in yeast. 2004. Cell. 116(3):405-15. PMID: 15016375
  2. Kari B, Lussenhop N, Goertz R, Wabuke-Bunoti M, Radeke R, Gehrz R. Characterization of monoclonal antibodies reactive to several biochemically distinct human cytomegalovirus glycoprotein complexes. 1986. J. Virol. 60:345-352. PMID: 3021969

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