This mouse IgG2a monoclonal antibody recognizes human c-Myc and was generated against a synthetic peptide corresponding to residues 408-420 of human c-Myc.
The c-Myc and N-Myc oncogenes are members of the Myc family of transcription factors that regulate cell proliferation and apoptosis. c-Myc is expressed in proliferating tissues and increased c-Myc expression is found in many cancers. N-Myc is amplified in a proportion of neuroblastoma patients. Myc (c-Myc) is a regulator gene that codes for a transcription factor is believed to regulate expression of 15% of all genes. Mutated c-myc leads to the unregulated expression of many genes, some of which are involved in cell proliferation and results in the formation of cancer.
From a laboratory at Cancer Research Technology.
Part of The Investigator's Annexe program.
|Name:||Anti c-Myc (9E11) monoclonal antibody|
|Clone Name:||9 E11|
|Immunogen:||Residues 408-420. AEEQKLISEEDL.|
|Purity:||Protein G purified|
|Buffer:||PBS, 0.05% (w/v) Sodium Azide|
|Tested Applications:||Frozen, Immunoprecipitation, Paraffin embedded|
|Storage:||Store at 4C|
If you publish research with this product, please let us know so we can cite your paper.