Anti-WWOX [12G5] Antibody

WW domain containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a WW domain containing oxidoreductase protein which contains two WW domains and a short-chain dehydrogenase/reductase domain (SRD). The highest normal expression of this protein is detected in hormonally regulated tissues such as testis, ovary, and prostate. This expression pattern and the presence of an SRD domain suggest a role for this protein in steroid metabolism. The encoded protein is more than 90% identical to the mouse protein, which is an essential mediator of tumor necrosis factor-alpha-induced apoptosis, suggesting a similar, important role in apoptosis for the human protein. In addition, there is evidence that this gene behaves as a suppressor of tumor growth.

From a laboratory at Harvard University.

The Investigator's Annexe Part of The Investigator's Annexe program.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
EF0008
Anti-WWOX [12G5] Antibody
100ug 4-6 weeks
Regular Price:$279.00
On Sale:
Specifications

Product Type: Antibody
Name: Anti-WWOX (12G5)
Accession ID: Q9NZC7
Host: Rat
Isotype: IgG
Clonality: Monoclonal
Clone Name: 12G5
Specificity: WWOX
Immunogen: Bacterial fusion protein
Format: Liquid
Purification Method: Protein G affinity purified
Buffer: PBS, 0.05% (w/v) Sodium Azide
Tested Applications: WB, ELISA
Concentration: 1mg/mL
Amount: 100uL
Storage: Store at 4C
Shipped: Cold packs

Provider
From a laboratory at Harvard University.
References

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