Anti-Caspase 8 [1H10] Antibody

This IgG2a rat monoclonal antibody was generated against a full length bacterial fusion protein and recognizes human caspase 8.

Caspase 8, an enzyme encoded by the CASP8 gene, is a member of the cysteine-aspartic acid protease family. Sequential activation of the caspases is critical for cell apoptosis. Caspase 8 acts upon caspases 3 and 7 following death receptor stimulation.

From a laboratory at Harvard University.

The Investigator's Annexe Part of The Investigator's Annexe program.

Catalog Number Product Size AVAILABILITY Price Qty
EF0006
Anti-Caspase 8 [1H10] Antibody
100ug In stock
Regular Price:$254.00
Specifications

Product Type: Antibody
Name: Anti-Caspase 8 (1H10)
Host: Rat
Isotype: IgG2a
Clonality: Monoclonal
Clone Name: 1H10
Specificity: Caspase 8 (human)
Immunogen: Bacterial fusion protein(full length)
Format: Liquid
Purity: Protein G affinity purified
Tested Applications: WB, ELISA, IHC
Concentration: 1mg/mL
Amount: 100uL
Storage: Store at 4C
Shipped: Cold packs

Provider
From a laboratory at Harvard University.
References
  1. Toshiyuki Nakagawa et al. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-ß. Nature, Vol 403, 2 January 2000
  2. Ivelisse Sanchez et al. Caspase-8 Is Required for Cell Death Incuced by Expanded Polyglutamine Repeats. Neuron, Vol. 22, 623-633, March 1999
  3. Honglin Li et al. Cleavage of Bid by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis. Cell, Vol. 94, 491-501, August 21, 1998

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