This IgG2a rat monoclonal antibody was generated against the bacterial fusion protein p20 and recognizes human caspase 10.
Caspase 10, an enzyme encoded by the CASP10 gene in humans, is a member of the cysteine-aspartic acid protease family. Sequential activation of caspases is critical for cell apoptosis. Caspase 10 cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in CASP10 are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome.
From a laboratory at Harvard University.
Part of The Investigator's Annexe program.
|Name:||Anti-Caspase 10 (25C2)|
|Specificity:||Caspase 10 (human)|
|Immunogen:||Bacterial fusion protein (p20)|
|Purity:||Protein G affinity purified|
|Tested Applications:||WB, ELISA|
|Storage:||Store at 4C|
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