Anti-E2F6 [LLF6-2] Antibody

This mouse monoclonal antibody was generated against human E2F6 (full length, 6X His-tagged) and recognizes both human and mouse E2F6.

E2F6 is a winged helix transcription factor important for regulating the expression of genes encoding proteins required for meiosis, cell cycle exit and skeletal patterning. E2F6 also interacts with members of the Bmi1 containing polycomb group complex and predominantly functions as a repressor of transcription.

From a laboratory at Massachusetts Institute of Technology.

The Investigator's Annexe Part of The Investigator's Annexe program.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
EC0002
Anti-E2F6 [LLF6-2] Antibody
100ug In stock
Regular Price:$328.00
On Sale:
Specifications

Product Type: Antibody
Name: E2F6 monoclonal antibody
Host: mouse
Isotype: IgG
Clonality: Monoclonal
Clone Name: LLF6-2
Specificity: human, mouse
Immunogen: Antibody was raised against 6x His-tagged full length human E2F6, purified from bacteria
Format: Liquid
Purity: Protein G purified
Tested Applications: ELISA, Western Blot, Immunoprecipitation, Gel Supershift Assay
Concentration: 1mg/mL
Amount: 100uL
Storage: +4C or -20C (avoid repeated freeze / thaw cycles)
Shipped: Cold packs

Data

Immunoprecipitation

Human ML-1 cell lysates were immunoprecipitated with control, E2F6 (from LLF6-1), or RYBP antibodies and resolved by SDS/PAGE, then probed by E2F6 (from LLF6-2) antibody.

Provider
References
  1. Courel M, Friesenhahn LB, Lees JA (2008) E2f6 an Bmi1 cooperate in axial skeletal development. Dev Dyn. (237): 1232-1242
  2. Trimarchi JM, Fairchild B, Wen J, Lees JA (2001) The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex. Proc. Natl. Acad. Sci. USA 98(4): 1519 - 24

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