This mouse monoclonal antibody was generated against human E2F6 (full length, 6X His-tagged) and recognizes both human and mouse E2F6.
E2F6 is a winged helix transcription factor important for regulating the expression of genes encoding proteins required for meiosis, cell cycle exit and skeletal patterning. E2F6 also interacts with members of the Bmi1 containing polycomb group complex and predominantly functions as a repressor of transcription.
From a laboratory at Massachusetts Institute of Technology.
Part of The Investigator's Annexe program.
|Name:||E2F6 monoclonal antibody|
|Immunogen:||Antibody was raised against 6x His-tagged full length human E2F6, purified from bacteria|
|Purity:||Protein G purified|
|Tested Applications:||ELISA, Western Blot, Immunoprecipitation, Gel Supershift Assay|
|Storage:||+4C or -20C (avoid repeated freeze / thaw cycles)|
Human ML-1 cell lysates were immunoprecipitated with control, E2F6 (from LLF6-1), or RYBP antibodies and resolved by SDS/PAGE, then probed by E2F6 (from LLF6-2) antibody.
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