This rabbit polyclonal antibody was raised against fusion protein and recognizes human, mouse and rat ATP Binding Cassette Subfamily D Member 2 (ABCD2).
ABCD2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies and this protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. Diseases associated with ABCD2 include Adrenoleukodystrophy and Demyelinating Disease.
From the laboratory of Greg A. Graf, PhD, University of Kentucky.
|Molecular Weight:||78 kDa|
|Reactivity:||Mouse, Rat and Human|
|Buffer:||50% glycerol, 50mM tris (pH 7.4) and 0.01% azide|
|Tested Applications:||WB (1:2000), IF (1:200), IEM (1:50)|
Immunofluorescence Microscopy and Immunoblot Analysis of D2 Protein in Cultured Cells.
(A) Cells were transfected with a plasmid containing a cDNA encoding mouse D2. Cells were processed for indirect immunofluorescence microscopy using the polyclonal D2 antibody. Inset: lysates from cells transfected with control plasmid (V) and D2 were analyzed by SDS-PAGE and immunoblotting. (B) Total membranes were prepared from adipose collected from wild-type and D2-deficient (D2-/-) mice and analyzed by immunoblotting with the D2 antibody.
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