Salutaridine synthase CYP719B1 [EC:188.8.131.52] produced in Sf9 insect cells is a cytochrome P450 enzyme from Papaver somniferum that is able to convert the substrate (R)-reticuline to salutaridine. This enzyme functions in the morphine biosynthetic pathway.
From the laboratory of Toni M. Kutchan, PhD, and Megan Augustin, Donald Danforth Plant Science Center.
|Molecular Weight:||56,498 Da|
|Buffer:||100 mM tricine pH 7.5/ 5 mM thioglycolic acid|
|Comments:||This enzyme requires the addition of NADPH for catalysis. Produced in Sf9 insect cells in conjunction with cytochrome P450 reductase from Eschscholzia californica and 2 mg/l hemin. Sf9 cells are permeabilized by the storage buffer|
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